According to the tutorial at 
http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/WhiteMatterEdits, we should 
be looking for these holes in the white surface, but when I looked at my 
processed data using tkmedit SUBJECT brainmask.mgz -aux wm.mgz -surfs, I saw 
many such holes.  They seem to be ubiquitous throughout all 20 of the brains I 
have processed.  Some might be true mistakes in the white matter surface, but I 
thought maybe some might just be holes that appear because of the shape of 
sulci moving through 3D space.    Or perhaps my Talairach is off?  Is there any 
material that instructs how to tell the difference between holes which need to 
be fixed and those that don't?  

Thank you,
Vincent

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