I think many have better scans than 1mm. Right now I'm using 0.7mm iso with
decent snr, and am collecting 2 scans (about 7 min each), and on most
slices I can see internal structural detail. It does seem a shame that all
this detail is not used for hippo-subfield segmentation.
-
Joshua Lee
Graduate Student
Center for Mind and Brain &
Department of Psychology
University of California, Davis
530.747.3805


On Tue, Feb 7, 2012 at 11:38 AM, Koen Van Leemput
<k...@nmr.mgh.harvard.edu>wrote:

> Hi Oliver,
>
> You're right: internally we're upsampling the images to 0.5mm
> isotropic resolution, so if you had acquired 0.5mm isotropic images
> from the start, that would actually be much better (provided you don't
> simply trade off SNR for increased image matrix size). The catch with
> this is that the scripts I put in FreeSurfer will only work out of the
> box on FreeSurfer-reformatted 1mm resolution, so you'd need to tweak
> things a bit to get it working.
>
> Hope this helps,
>
> Koen
>
>
>
> On Thu, Feb 2, 2012 at 3:46 AM, Grimm, Oliver
> <oliver.gr...@zi-mannheim.de> wrote:
> >
> >
> > Dear FreeSurfer-User,
> >
> >
> >
> > some of my questions are mentioned in some older postings, but I still
> > struggle with some basic questions. We are planning to use the new
> > hippocampal subfield segmentation of FS 5.1 with 3 T Siemens TRIO with 32
> > channel head coil. Still, I do not fully understand how to optimize our
> > image processeing pipeline:
> >
> > Freesurfer works internally with 1x1x1 mm3 but the hippocampal segmenat
> uses
> > a higher res. of 0.5 x 0.5 x 0.5 mm3. So should we instead use a higher
> > resolution for the hippocampal subfield seg.?
> > I understand that the recent FS version is not working well with high
> > resolution images, e.g. the atlases are not provided in a higher res,
> > however the hippocampal subfield segmentation seems to make use of
> > aseg.stats. So is is possible at all to use the FS-pipleine in this case
> > (hippocampal subfields)?
> > Instead of using a high resolution image, we could average over several
> > pictures. When I tried this, I had the visual impression, that there was
> > almost no gain in this, the volume estimates were bouncing within a
> range of
> > 10% but did not converge when averaging from scan 1-5 to a specific
> value.
> > So is it necessary for a good quality to average images when using
> > hippocampal subfield segmentation ?
> >
> > Thanks for your efforts!
> >
> > Best,
> >
> >
> >
> >
> >
> > Dr. med. Oliver Grimm
> > Zentralinstitut für Seelische Gesundheit
> >
> > www.zi-mannheim.de
> >
> > SNiP | Systems Neuroscience in Psychiatry
> >
> > 68159 Mannheim
> >
> > Germany
> >
> >
> >
> > Tel:     +49-621-1703-6341
> > Fax:    +49-621-1703-6305
> > email oliver.gr...@zi-mannheim.de
> >
> >
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