bump :)

any feedback on this would be very much appreciated.  Thank you!

Jeff

On Mon, Jan 23, 2012 at 6:56 PM, Jeff Sadino <jsadino.que...@gmail.com> wrote:
> Hello,
>
> Thank you Nick, Martin, and Doug for your previous feedback about ICV.
>  I have a couple more questions that I am hoping you could clarify for
> me.
>
> To verify my ICV value, some pages on the mailing list and wiki say to
> use this command:
> tkregister2 --s subject --fstal --surf
>
> Other places say to use this:
> tkregister2 --xfm talairach.xfm --targ
> $FREESURFER_HOME/average/RB_all_withskull_2008-03-26.gca --mov
> ../nu_noneck.mgz --reg junk
>
> However, on this wiki page
> (http://surfer.nmr.mgh.harvard.edu/fswiki/eTIV), it says that post
> fs4.2.0, the template is this file:
> 711-2C_as_mni_average_305.4dfp.img.  In the first tkregister2 command
> above, doesn't the --fstal flag use the talairach template?  But
> shouldn't it be using the 711 template?  And since I am using fs5.0.0,
> does that mean that I should not be using the RB template?
> Ultimately, what is the correct way to verify the ICV in fs 5.0.0?
>
> Thank you very much,
> Jeff Sadino
>
> On Mon, Mar 1, 2010 at 7:57 AM, Douglas N Greve
> <gr...@nmr.mgh.harvard.edu> wrote:
>> It's hard to tell from the coronal, but it looks ok. The problem is more
>> visible in the sagittal.
>>
>> doug
>>
>> Jeff Sadino wrote:
>>>
>>> Hello Doug,
>>>
>>> I loaded up the tkregister2 program and I think I see some poor
>>> transformations.  I've never really used it before though.  Am I just
>>> looking at whether or not the green line lines up with the target image wm?
>>>  Can you look at my pictures real quick?  040002_S04_test is from fs4 that
>>> is having problems.  040002_S04 is from fs3 and has a good icv value.  Some
>>> of the blank spots are from my graphics drivers and unrelated to fs.
>>>  tkregister2 also said the determinant of 040002_S04_test was 1.49544.
>>>
>>> Martin,
>>>
>>> Thank you for the idea.  I did this, and got a much better icv.  On fs3,
>>> where the icv was good, the number was 1,767,481.  On fs4, it was 1,302,696.
>>>  Using your idea on fs4, it was 1,819,485.
>>>
>>> Thank you so much to everyone for your help!
>>> Jeff
>>>
>>> On Thu, Feb 25, 2010 at 8:53 PM, Martin Kavec <martin.ka...@gmail.com
>>> <mailto:martin.ka...@gmail.com>> wrote:
>>>
>>>    Hi Jeff,
>>>
>>>    I see this relatively often. Eventhough the talairach registration
>>>    is fine, the
>>>    ICV is underestimated. In this case I take old ICV, which helps.
>>>
>>>    mri_segstats --subject $MYSUBJECT --old-etiv-only
>>>
>>>    This is in 99% of these cases a cure. This is not just a blind
>>>    attempt. In
>>>    these cases I then compare each ICV normalized aseg volume against
>>>    an age
>>>    matched group and only if the old-etiv-only ICV gives better
>>>    estimates I use
>>>    it.
>>>
>>>    Cheers,
>>>
>>>    Martin
>>>
>>>    On Thursday 25 February 2010 23:05:10 Jeff Sadino wrote:
>>>    > Thanks Doug.  That is very good news to hear!
>>>    >
>>>    > Maybe I spoke too soon about fixing the problem.  I looked at 4 more
>>>    > subjects, and even though the icv value is unique, its magnitude
>>>    seems
>>>    > wrong.  Often times, it is smaller than the BrainSegVol, which
>>>    doesn't make
>>>    > much sense and it is also low overall.
>>>    >
>>>    >
>>>    > # subjectname 090167_F01
>>>    > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels,
>>>    1639959,
>>>    > unitless
>>>    > # Measure BrainMask, BrainMaskVol, Brain Mask Volume,
>>>    1639959.000000, mm^3
>>>    > # Measure BrainSegNotVent, BrainSegVolNotVent, Brain
>>>    Segmentation Volume
>>>    > Without Ventricles, 1289194.000000, mm^3
>>>    > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation
>>>    Voxels,
>>>    > 1299686, unitless
>>>    > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume,
>>>    1299686.000000,
>>>    > mm^3
>>>    > # Measure IntraCranialVol, ICV, Intracranial Volume,
>>>    1105595.114652, mm^3
>>>    >
>>>    > # subjectname 090182_S01
>>>    > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels,
>>>    1599981,
>>>    > unitless
>>>    > # Measure BrainMask, BrainMaskVol, Brain Mask Volume,
>>>    1599981.000000, mm^3
>>>    > # Measure BrainSegNotVent, BrainSegVolNotVent, Brain
>>>    Segmentation Volume
>>>    > Without Ventricles, 1199694.000000, mm^3
>>>    > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation
>>>    Voxels,
>>>    > 1205382, unitless
>>>    > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume,
>>>    1205382.000000,
>>>    > mm^3
>>>    > # Measure IntraCranialVol, ICV, Intracranial Volume,
>>>    1114008.197334, mm^3
>>>    >
>>>    > # subjectname 090187_F01
>>>    > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels,
>>>    1826694,
>>>    > unitless
>>>    > # Measure BrainMask, BrainMaskVol, Brain Mask Volume,
>>>    1826694.000000, mm^3
>>>    > # Measure BrainSegNotVent, BrainSegVolNotVent, Brain
>>>    Segmentation Volume
>>>    > Without Ventricles, 1381871.000000, mm^3
>>>    > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation
>>>    Voxels,
>>>    > 1388801, unitless
>>>    > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume,
>>>    1388801.000000,
>>>    > mm^3
>>>    > # Measure IntraCranialVol, ICV, Intracranial Volume,
>>>    1307759.303915, mm^3
>>>    >
>>>    > # subjectname 100014_F01
>>>    > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels,
>>>    1948121,
>>>    > unitless
>>>    > # Measure BrainMask, BrainMaskVol, Brain Mask Volume,
>>>    1948121.000000, mm^3
>>>    > # Measure BrainSegNotVent, BrainSegVolNotVent, Brain
>>>    Segmentation Volume
>>>    > Without Ventricles, 1467582.000000, mm^3
>>>    > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation
>>>    Voxels,
>>>    > 1488088, unitless
>>>    > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume,
>>>    1488088.000000,
>>>    > mm^3
>>>    > # Measure IntraCranialVol, ICV, Intracranial Volume,
>>>    1637915.031593, mm^3
>>>    >
>>>    > # subjectname 040002_S04_test
>>>    > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels,
>>>    1774481,
>>>    > unitless
>>>    > # Measure BrainMask, BrainMaskVol, Brain Mask Volume,
>>>    1774481.000000, mm^3
>>>    > # Measure BrainSegNotVent, BrainSegVolNotVent, Brain
>>>    Segmentation Volume
>>>    > Without Ventricles, 1288022.000000, mm^3
>>>    > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation
>>>    Voxels,
>>>    > 1312132, unitless
>>>    > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume,
>>>    1312132.000000,
>>>    > mm^3
>>>    > # Measure IntraCranialVol, ICV, Intracranial Volume,
>>>    1302696.178406, mm^3
>>>    >
>>>    > I had also done 040002_S04 in fs 3.0.5, and this is the result:
>>>    > # subjectname 040002_S04
>>>    > # BrainMaskFile mri/brainmask.mgz
>>>    > # BrainMaskFileTimeStamp 2008/29/08 15:44:46
>>>    > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels,
>>>    1753272,
>>>    > unitless
>>>    > # Measure BrainMask, BrainMaskVol, Brain Mask Volume,
>>>    1753272.000000, mm^3
>>>    > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation
>>>    Voxels,
>>>    > 1310474, unitless
>>>    > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume,
>>>    1310474.000000,
>>>    > mm^3
>>>    > # Measure IntraCranialVol, ICV, Intracranial Volume,
>>>    1767481.547316, mm^3
>>>    >
>>>    > All of the values are similar except the icv.  Do you guys have
>>>    any ideas
>>>    > where I can look for the answer?
>>>    >
>>>    > Thank you very much,
>>>    > Jeff
>>>    >
>>>
>>>
>>
>> --
>> Douglas N. Greve, Ph.D.
>> MGH-NMR Center
>> gr...@nmr.mgh.harvard.edu
>> Phone Number: 617-724-2358 Fax: 617-726-7422
>>
>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>> FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>>

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