Hi Doug and many thanks for your reply and help. If blue means neg, red/yellow 
is positive does this means that where is blue we have a decrease in FA for 
while positive means an increase? 

How I know if there is a decrease in controls versus patients and not opposite 
(FA decreases in patients versus controls)?


Is my  C = +1.00000 -1.00000 correct if I am interested only in group 
differences and I want to eliminate the age.

Also can you please take a look on my y (please see the attached file) to 
confirm if is correct?


Thank you very much and have a great weekend!
Antonella


________________________________
 From: Douglas N Greve <gr...@nmr.mgh.harvard.edu>
To: Antonella Kis <ator...@yahoo.com>; freesurfer 
<freesurfer@nmr.mgh.harvard.edu> 
Sent: Friday, January 13, 2012 2:13 PM
Subject: Re: Fw: [Freesurfer] FA and non_FA group analysis
 
Look at the original sig map. This will be signed (blue and red/yellow), with 
blue being neg, red/yellow being positive.
doug

Antonella Kis wrote:
> Dear Doug,
> 
> I am forwarding Bruce answer to my question since he directed me to you.
> 
> I need some help regarding my FA and non-FA group analysis study. I am not 
> using tracula. I used the dt_recon and I have done the registration for my FA 
> data on the cvs space using the mri_cvs_register.  I used the GLM group 
> analysis method after I concatenate FA from individuals into one file and 
> used mri_glmfit-sim with the option grf as you recommended me some time ago:
> 
>  mri_glmfit-sim \
>    --glmdir Group_Analysis.glmdir \
>    --grf 2 neg \
>    --cwpvalthresh .025 \
>    --overwrite
>   to cache the significant clusters after multiple comparisons so I have the 
>uncorrected and corrected significant map but I don't know how I can see if  
>my FA is increasing or decreasing in controls
>  group versus patients group.
>  
> I will appreciate any help/suggestion.
> 
>  Thank you.
>  Antonella
> 
> ----- Forwarded Message -----
> *From:* Bruce Fischl <fis...@nmr.mgh.harvard.edu>
> *To:* Antonella Kis <ator...@yahoo.com>
> *Cc:* "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
> *Sent:* Thursday, January 12, 2012 11:16 AM
> *Subject:* Re: [Freesurfer] FA and non_FA group analysis
> 
> Hi Antonella
> 
> I think this is a question for Doug.
> 
> 
> cheers
> Bruce
> On Thu, 12 Jan 2012, Antonella Kis
> wrote:
> 
> >
> >
> > Dear Bruce,
> >
> > Once again many thanks for helping.I am not using tracula. I used the 
> > dt_recon and I have done the registration for my FA data on the cvs space 
> > using the mri_cvs_register.  I used the GLM group
> > analysis method after I concatenate FA from individuals into one file and 
> > used
> >
> >
> > mri_glmfit-sim \
> >   --glmdir Group_Analysis.glmdir \
> >   --grf 2 neg \
> >   --cwpvalthresh .025 \
> >   --overwrite
> >
> > to cache the significant clusters after multiple comparisons so I have the 
> > uncorrected and corrected significant map but I don't know how I can see 
> > if  my FA is increasing or decreasing in controls
> > group versus patients group.
> >
> >
> > Please advise me.
> >
> > Thank you.
> > Antonella
> >
> >
> >
> >
> >
> >
> >
> _______________________________________________
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> 
> 
> The information in this e-mail is intended only for the person to whom it is
> addressed. If you believe this e-mail was sent to you in error and the e-mail
> contains patient information, please contact the Partners Compliance HelpLine 
> at
> http://www.partners.org/complianceline . If the e-mail was sent to you in 
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> 

-- Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 Fax: 617-726-7422

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