Hi Andreia, I don't think this is a problem for the GM volume (ie, parts 
of the amyg or hippo getting counted twice). The thickness should be 0 
in those areas, so they should not contribute to GM volume. The 
computation of the WM volume is done in a different way (still surface 
based) but automatically excludes subcortical structures.
doug

_andre...@sapo.pt wrote:
> Hello,
>
> Recalling these emails:
>
> "The methods are somewhat different. For the value in the aseg.stats
> table, the method is to compute the total volume inside the pial surface
> and subtract the total volume inside the white surface. For
> mris_anatomical_stats, the method is to compute the thickness times area
> of each vertex. This method will probably underestimate the total volume
> because it uses the area of the white surface when it should use the
> area of the surface in the middle between the white and pial surfaces.
> I've added this to the list of known issues on our release page.
>
> doug
>
> Alexopoulos, Dimitrios wrote:
>   
>> I have generated surfaces using the the centos4 build (version 5.0)
>> and want to confirm that my surface-based GM and WM volumes are correct.
>> For the surface-based GM calculation I originally used  
>> 'mris_anatomical_stats -l lh.cortex.label subjectID hemi'
>> (run from within the 'label' subdirectory) and for WM i used  
>> 'mris_wm_volume subjectID hemi' (run from within
>> the 'surf' subdirectory).
>> When I add the calculated left/right cortical volumes, I get a total  
>> that is different from what is output in
>> the 'aseg.stats' file, which in version 5.0 is noted to contain  
>> total surface-based GM volume
>> (Cortex, CortexVol: Total cortical gray matter volume (based on  
>> surface-stream).
>>  What are the correct GM and WM surface-based volumes?
>> Thanks. Jim"
>>     
>
>
> I question came up to me:
>
> The surfaces in the hippocampus/amygdala are inaccurate and should be  
> ignored. However, in version 5.0 the cortical volume is surface-based,  
> thus it takes into account the surfaces in the hippocampus/amygdala,  
> is this correct?
>
> If so, it is expected that an error is introduced in the surface-based  
> calculation of cortical volume. Has anyone checked the influence of  
> this error? Or FS compensates for the inaccuracy of the surface  
> estimation of these regions somehow?
>
> Thanks!
>
> Andreia
>
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>
>   

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

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