Hi Doug,

Thanks for the quick reply.  I will re-run the mri_segstats as below to get
the BrainSegNotVent volumes for consistency with the previous version.

Just for my own understanding using the default output aseg.stats from
recon-all, could whole brain parenchymal volume be calculated as  [(total
GM, total cortical WM, cerebellar GM, cerebellar WM + brain-stem)-2*(left
lateral ventricle + left Inf Lat Vent + right lateral ventricle+ right inf
lat vent) - CSF)]? I'm assuming that since both the white matter and pial
surfaces include the lateral ventricle, the lateral ventricular volume needs
to be subtracted, while the 3rd and 4th ventricles are not included in the
surfaces and therefore would not need to be subtracted?

Kind regards,
Cheryl


On 11-12-14 12:45 PM, "Douglas N Greve" <gr...@nmr.mgh.harvard.edu> wrote:

> Hi Cheryl,
> You can regenerate the asseg.stats file with BrianVolNotVent with:
> 
> cd $SUBJECTS_DIR/yoursubject
>  mri_segstats --subject yoursubject --seg mri/aseg.mgz --sum
> stats/aseg.stats --pv mri/norm.mgz --empty --excludeid 0 --excl-ctxgmwm
> --supratent --subcortgray --in mri/norm.mgz --in-intensity-name norm
> --in-intensity-units MR --etiv --surf-wm-vol --surf-ctx-vol --totalgray
> --ctab /usr/local/freesurfer/dev/ASegStatsLUT.txt  --brain-vol-from-seg
> 
> This is the same command that generated the existing aseg.stats file
> with "--brain-vol-from-seg" added.
> 
> doug
> 
> 
> 
> 
> 
> Cheryl McCreary wrote:
>> Hi Freesurfer experts,
>> 
>> I would like to determine brain parenchymal fraction (ie brain tissue
>> volume/estimated ICV) as an estimate of global atrophy.  In previous
>> versions of FS, I used the BrianVolNotVent/ICV.  Is this correct?
>> 
>> I am now using freesurfer version 5.0.0 and BrainVolNotVent is not longer
>> available. 
>> 
>> My understanding is that the total gray matter and total cortical white
>> matter volumes are determined from the pial and white surfaces (thickness
>> *surface area).  Do these volumes include or exclude the ventricular
>> volumes? Can the total brain volume be calculated as the sum of the total
>> GM, total cortical WM, brain stem, cerebellar GM and WM minus the CSF.  Or
>> do the volumes of the ventricles need to be subtracted as well?
>> 
>> Thanks for your help.
>> 
>> Cheryl  
>>   

-- 
Cheryl McCreary
Research Assistant Professor
Seaman Family MR Research Centre
Foothills Medical Centre
1403 29th Street NW
Calgary, AB
T2N 2T9
Phone: (403) 944-8781
FAX: (403) 270-7907


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