Thanks Doug.  And good question that I've wondered about myself Jeff.

The part about the high-resolution volume that is created "under the
hood" explains why mris_wm_volume takes substantially longer to complete
than would be expected relative to just running `mris_volume Xh.white`
and then subtracting off some values from the aseg.stats

cheers,
-MH

On Fri, 2011-12-02 at 12:07 -0500, Douglas N Greve wrote:
> Hi Jeff, it's going to be tricker than that to get the exact value. For 
> the WM volume computation, there's yet another routine that is used. 
> This one creates a high-resolution volume to determine which voxels are 
> withing the WM surface. It then loops through the voxels within the WM 
> surface and counts the ones that have the following labels in the aseg:
>         case Left_Cerebral_Cortex:
>         case Right_Cerebral_Cortex:
>         case Left_Cerebral_White_Matter:
>         case Right_Cerebral_White_Matter:
>         case Left_WM_hypointensities:
>         case Right_WM_hypointensities:
>         case CC_Posterior:
>         case CC_Mid_Posterior:
>         case CC_Central:
>         case CC_Mid_Anterior:
>         case CC_Anterior:
> Note that the cortical labels are there to catch the partially volumed 
> voxels.
> hope this helps
> doug
> 
> 
> 
> Jeff Sadino wrote:
> > Thank you Doug for your answer.  After reading the wiki more, it has 
> > led me to another question.
> >
> > I am trying to duplicate the White Matter value from aseg.stats using 
> > FreeSurfer 5.0.0.  The value from aseg.stats is 220804 (as it is also 
> > when running mris_wm_volume).  By hand, when I run mris_volume subject 
> > lh.white, I get 239035.  From this, I subtract:
> > Left-Lateral-Ventricle
> > Left-Inf-Lat-Vent
> > Left-vessel
> > Left-Thalamus-Proper
> > Left-Caudate
> > Left-Putamen
> > Left-Pallidum
> > Left-Accumbens-area
> > Left-VentralDC
> > Left-choroid-plexus
> > and then I am left with 209832.  Can someone please give more detail 
> > about how or which areas mris_wm_volume excludes?
> >
> > Thank you very much,
> > Jeff
> >
> > On Wed, Nov 30, 2011 at 7:46 AM, Douglas N Greve 
> > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
> >
> >     Hi Jeff, the total cortical gray matter is based on the volume
> >     between the white and pial surfaces. The other structures you
> >     mention below are based on the automatic volume segmentation.
> >     doug
> >
> >     Jeff Sadino wrote:
> >
> >         Hello,
> >
> >         Thank you Bruce and Doug for your answers to my previous
> >         question about a bad talairach.lta file.  I am now grabbing
> >         volumes using fs5.0.0 and would like to ask for clarification.
> >          On the Morphometry Stats page at
> >         http://surfer.nmr.mgh.harvard.edu/fswiki/MorphometryStats, it
> >         says that the cortex is based on the pial surface.  I am
> >         wondering what this includes.  I loaded up the pial surface in
> >         tkmedit along with aseg.mgz.  It looks like the following
> >         regions are completely outside the pial surface: cerebellum,
> >         4th ventricle, Brain-Stem, optic chiasm.  Is it correct that
> >         these regions are excluded?  And then it looks like the
> >         hippocampus, amygdala, and inferior-lateral-ventricle are only
> >         halfway outside the pial surface.  Is that correct?  If it is,
> >         then is there a recommended way to exclude the hippocampus,
> >         amygdala, and inferior-lateral-ventricle regions in the
> >         cortical gray matter?  Do these regions get properly accounted
> >         for in the subcortical gray calculation?
> >
> >         And then for the white matter, the webpage says that it is
> >         based on the white surface.  Looking at the white surface
> >         (lh.white), all of the subcortical gray matter and ventricles
> >         are enclosed in the surface.  Can someone explain how the
> >         subcortical gray gets excluded?
> >
> >         Finally, for the SubCortGray reported in aseg.stats file, does
> >         that exclude the following areas:
> >         Left-Lateral-Ventricle
> >         Left-Inf-Lat-Vent
> >         3rd-Ventricle
> >         4th-Ventricle
> >         CSF
> >         Left-vessel
> >         Right-Lateral-Ventricle
> >         Right-Inf-Lat-Vent
> >         Right-vessel
> >         5th-Ventricle
> >         Left-Cerebellum-White-Matter
> >         Right-Cerebellum-White-Matter
> >         WM-hypointensities
> >
> >         What about the brain stem?  Why is the cerebellum Gray Matter
> >         included?  I ask because the only way I can get close to the
> >         SubCortGray by using the aseg file is by excluding those regions.
> >
> >         Once again, thank you for your invaluable help!
> >         Jeff Sadino
> >         
> > ------------------------------------------------------------------------
> >
> >         _______________________________________________
> >         Freesurfer mailing list
> >         Freesurfer@nmr.mgh.harvard.edu
> >         <mailto:Freesurfer@nmr.mgh.harvard.edu>
> >         https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
> >
> >
> >     -- 
> >     Douglas N. Greve, Ph.D.
> >     MGH-NMR Center
> >     gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
> >     Phone Number: 617-724-2358 <tel:617-724-2358> Fax: 617-726-7422
> >     <tel:617-726-7422>
> >
> >     Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> >     <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
> >     FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
> >     <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>
> >
> >
> >
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