Hi Joshua,

The version of the hippocampal subfield segmentation routines
currently in FreeSurfer will only work out of the box on the usual
FreeSurfer-resampled 1mm isotropic data. If you are technically
skilled, it should be possible to tweak things to make it work on
other data (we don't assume specific contrast properties and/or
acquisition sequences in the actual subfield segmentation algorithm).
We have a Matlab version of the code as well that might be a lot
easier to play with - please let me know if you're interested in that.

Koen


On Fri, Oct 14, 2011 at 1:46 PM, Joshua Lee <jki...@ucdavis.edu> wrote:
> Dear Experts,
>
> I've been collecting hi-res hippocampal scans with a 32 ch coil on a 3T
> Siemens Trio to manually segment hippocampal subfields. However, I wonder
> whether the protocol is appropriate for use with the new Freesurfer subfield
> segmentation tool.
>
> Specifically, our hi-res scan does not capture the entire brain, rather it
> acquires slices perpendicular to the long axis just for the length of the
> long axis axis. Can this scan be used for the new subfield
> auto-segmentation? Or does it require a whole-brain acquisition?
>
> We do acquire a 1 mm isotropic whole brain MPRage, but...
>
> Thanks for any info,
> Joshua
>
>
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