Hey Freesurfers,
I've been trying to register my FEAT data to my Freesurfer data via
reg-feat2anat in order to get V1 binary masks:

reg-feat2anat --->aparc/aseg2feat --->fslmaths.

 It seemed to work ok, and I extracted time series for my areas of interest
and ran a PPI analysis in FSL.  When reviewing my results I discovered that
for two people their brains were flipped 90 degrees around multiple axes
compared with the group.  So I decided to go back to reg-feat2anat and
manually edit the registration of all my subjects.  For most people the
edits were extremely minor.  For the 2 highly problematic ones, appropriate
rotations were made.

When I returned to my PPI analysis, I found that now all of my brains are
rotated by at least 45 degrees sometimes about multiple axes.  I am
thoroughly perplexed.

Does anyone know what might have gone wrong?

Thanks.
Michelle
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