Did you check to see whether the cerebellum (or some large bit of skull 
or brain stem) are still attached?
doug

Kevin Liu wrote:
> Hi,
>
> I'm relatively new to the FreeSurfer program and have mostly worked 
> with processing adult brains. I am currently working on reconstructing 
> images of young children under 5 and am consistently running into the 
> same error for the two subjects I am running during mris_fix_topology. 
> The error is as follows:
>
> 153 defects found, arbitrating ambiguous regions...
> analyzing neighboring defects...
>       -merging segment 19 into 4
>       -merging segment 28 into 7
>       -merging segment 44 into 7
>       -merging segment 43 into 7
>       -merging segment 59 into 7
>       -merging segment 63 into 7
>       -merging segment 24 into 8
>       -merging segment 25 into 17
>       -merging segment 21 into 18
>       -merging segment 67 into 30
>       -merging segment 78 into 30
>       -merging segment 38 into 33
>       -merging segment 79 into 73
>       -merging segment 85 into 77
>       -merging segment 113 into 77
>       -merging segment 88 into 77
>       -merging segment 95 into 77
>       -merging segment 97 into 77
>       -merging segment 93 into 87
>       -merging segment 91 into 90
>       -merging segment 135 into 117
>       -merging segment 136 into 117
>       -merging segment 141 into 126
>       -merging segment 146 into 140
>       -merging segment 149 into 142
> 128 defects to be corrected
> 0 vertices coincident
> reading input surface /home/local/SOC/kcl388/wong_
> lab/labmridata/FreeSurfer/CMH-3305/surf/lh.qsphere.nofix...
> reading brain volume from brain...
> reading wm segmentation from wm...
> Computing Initial Surface Statistics
>       -face       loglikelihood: -9.7664  (-4.8832)
>       -vertex     loglikelihood: -7.0295  (-3.5147)
>       -normal dot loglikelihood: -3.5134  (-3.5134)
>       -quad curv  loglikelihood: -6.0484  (-3.0242)
>       Total Loglikelihood : -26.3577
>
> CORRECTING DEFECT 0 (vertices=281, convex hull=141)
> After retessellation of defect 0, euler #=-62 (115680,331866,216124) : 
> difference with theory (-125) = -63
>
> CORRECTING DEFECT 1 (vertices=100, convex hull=64)
> After retessellation of defect 1, euler #=-61 (115689,331920,216170) : 
> difference with theory (-124) = -63
>
> CORRECTING DEFECT 2 (vertices=12, convex hull=20)
> After retessellation of defect 2, euler #=-60 (115690,331929,216179) : 
> difference with theory (-123) = -63
>
> CORRECTING DEFECT 3 (vertices=395, convex hull=187)
> After retessellation of defect 3, euler #=-59 (115735,332152,216358) : 
> difference with theory (-122) = -63
>
> CORRECTING DEFECT 4 (vertices=7865, convex hull=2299)
>
>
>
>
> The defects never completely correct, and the program just hangs on 
> correcting one of the defects (in this case 'DEFECT 4'). Do you have 
> any suggestions as to where to go from here? I have checked talairach 
> and done skull stripping edits, none of which seemed to have worked.
>
> Best,
> Kevin
>
>
> -- 
> Kevin Liu
> MD Candidate 2014
> Feinberg School of Medicine 
>
>
>
>
> -- 
> Kevin Liu
> MD Candidate 2014
> Feinberg School of Medicine 
>
> ------------------------------------------------------------------------
>
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> Freesurfer@nmr.mgh.harvard.edu
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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