Hi Ignacio,

the thickness is definitely affected by factors such as sequence type, field strength and acquisition parameters (not to mention age, maybe gender, etc...) so I think you need to acquire your own control(s) on a matched acquisition.

cheers.
Bruce

 On Tue, 5 Jul 2011, Ignacio Letelier wrote:

Hi Bruce,

Otherwise, is it possible to simply compare my T1 brain acquisition  (with
dysplasia suspicion) with a 'normal template' (which maybe bert) to
determine whether there exist any  anomaly in the cortical thickness ? and,
is it possible to visualize these potential differences using a color map
scaling?

Thanks in advance-

Best regards.

Ignacio.

2011/7/3 Bruce Fischl <fis...@nmr.mgh.harvard.edu>
      Hi Ignacio,

      I see. You could do that, but I don't think it will show what
      you want. There is a big geometric component to the thickness -
      crowns are thick and fund are thin - so at the very least you
      might try including mean curvature as a covariate.


cheers
Bruce

On Fri, 1 Jul 2011, Ignacio Letelier wrote:

      Sorry I didn't realize since you have the same domain.

      Ok, Let's say I do know the mean cortical thickness value
      of a subject. Then
      is it possible know  what brain areas differ more from
      that mean value by
      using a color map visualization (I.e.  for example: red =
      higher deviations,
      deep blue = lower deviations)? So this way I can determine
      where there may
      exist some kind of dysplasia.

      Best regards.

      2011/7/1 Bruce Fischl <fis...@nmr.mgh.harvard.edu>
           can you post this kind of thing so others can answer?
      I still
           don't understand though. stdv of what?


      On Fri, 1 Jul 2011, Ignacio Letelier wrote:

           Let's say I want to know if there is a way to know
      where
           is the highest stdv in the same subject, using a
      color map
           visualization in qdec or something?

           Best regards.

           2011/7/1 Bruce Fischl <fis...@nmr.mgh.harvard.edu>
                Hi Ignacio

                you mean different from the median in that
      subject?
           Easy enough to do in matlab, but we don't have
      anything
           out of the box to do it

                cheers
                Bruce

           On Fri, 1 Jul 2011, Ignacio Letelier wrote:

                Hi forum

                Is it possible to get statistical maps of 
      cortical
           thickness differences in the same subject? I.e. to
      know
           what areas differ most from the median


                --
                Ignacio




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