corinna bauer wrote:
> Alright that should work. So do I use the pet.anat.nii files (from 
> mri_vol2vol) as the input pet file to the mri_compute_volume_fractions? 
No, use the pet volume. This does everything in the pet space.
> Also, has anyone published using this pv correction method that you 
> know of?
I don't know. I think this is how they do pvc in pet, but I really don't 
know the lit.
>
> An alternative method that I was thinking was to do something similar 
> to the cortical thickness correction Salat used and sample on either 
> side of the gray/white boundary and the gray/csf boundary and 
> calculate the ratio. Do you think this could account for the effects 
> of pv in pet?
David's method was not for doing pvc, and I would not use it for pet.

doug
>
> Corinna
>
> On Wed, Jun 8, 2011 at 1:44 PM, Douglas N Greve 
> <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
>
>     Actually, I think it only will affect the volume measurement for
>     each structure, so that's no good. There is not a flag to
>     mri_segstats that will do this. If you have a registration between
>     your native pet data and the FS anat, then you can use
>
>     mri_compute_volume_fractions regfile.dat pet.nii pvf
>     This will create pvf.{gm,wm,csf}.mgz
>
>     You can then correct the pet with something like
>     fscalc pet.nii div pvf.gm.mgz pet.pvf.nii
>
>     You can map the aparc+aseg into the pet space using mri_label2vol
>     (and the reg from above), then use mri_segstats with the files in
>     the native pet space.
>
>     doug
>
>     corinna bauer wrote:
>
>         Hi Doug,
>         I will give that a try. How will this account for the p.v. in
>         pet data? Does it remove the voxels that are mixed tissue
>         classes? Does it account for partial volume effects between
>         neighbouring grey matter structures?
>         Corinna
>
>         On Wed, Jun 8, 2011 at 1:06 PM, Douglas N Greve
>         <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>         <mailto:gr...@nmr.mgh.harvard.edu
>         <mailto:gr...@nmr.mgh.harvard.edu>>> wrote:
>
>            Hi Corinna,
>            try adding --pv mri/norm.mgz
>            doug
>
>            corinna bauer wrote:
>
>                Hi all,
>                I am wondering if partial volume is taken into account when
>                calculating average uptake values of pet data. I know that
>                aseg.stats takes partial volume into account and I am
>                wondering if there is something similar in place for
>         pet data?
>                From what I gather, most people when using FreeSurfer
>         correct
>                for partial volume effects by regressing out cortical
>                thickness, but no basis for this correction method has been
>                provided. Any insight would be appreciated.
>
>                n.b. to obtain the pet uptake values I used
>         mri_segstats --seg
>                mri/aparc+aseg.mgz --sum pet.segstats.dat --i $petanat
>         --ctab
>                rois.txt
>
>                Thank you,
>                Corinna
>              
>          
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>     MGH-NMR Center
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

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FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html

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