Hi John,
mri_glmfit-sim actually runs on the GLM dir created when you run 
mri_glmfit (it does not take a separate directory). It applies the 
correction to all the contrasts in the GLM dir, so you just need to set 
up a GLM with the contrast you want to correct.

doug

John Richey wrote:
> Dear freesurfer experts, 
>
> I have a question about the conceptual use of mri_glmfit-sim.  I wish to
> apply permutation based cluster-correction to my between-groups results
> (patients vs  controls), and it is not clear to me which volume should be
> the input for this type of simulation. 
>
> For example, the acceptable input for mri_glmfit-sim appears to be only the
> ".ces" map, which is not present in my between-groups directory, but only in
> my lower-level one-sample group means (osgm). This raises the question of
> whether to run the permutation algorithm 1) one time on the .ces map that
> results from the total sample OSGM (i.e. patients + controls), or 2)
> separately on OSGM for patients and then controls.  Probably I am mistaken
> but neither seem to be conceptually correct, as I am mainly interested in
> the cwp for clusters emerging in the between-groups contrast. 
>
> Any help would be greatly appreciated! 
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>
>
>   

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

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