Hi Elisabeth we have found that higher voxel resolution doesn't necessarily help, as it starts to reveal inhomogeneities in the gray matter due to laminar structure, so 1mm isotropic is probably best. One approach we have used is to acquire 1mm data, then higher resolution in a specific part of cortex, although this can be difficult to analyze due to differential distortions between the scans.
cheers Bruce On Mon, 9 May 2011, Wenger, Elisabeth wrote: > Dear Freesurfer experts, > > I am currently planning a study in which I want to investigate changes in > gray matter due to training on structural MR images. I heard some rumors that > although FreeSurfer can of course process images with different voxel sizes, > it always somehow "transforms" the voxel size to 1 x 1 x 1, irrespective of > the originally obtained image resolution. I've been wondering if something > has changed in this regard, that is, whether FreeSurfer is now capable of > maintaining a higher resolution (eg, 0.8 mm) throughout all the analysis > steps? > As I am looking for very very tiny changes I would like to acquire images > with 0.8mm resolution. But if FreeSurfer has to convert these images with the > help of some estimation processes at some point of the reconstruction, I > would rather like to acquire 1 x 1 x 1 images in the first place. > > Thank you so much for your help! > > All the best, > Elisabeth > > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
