Thanks very much Doug, I'll use this method.

In case it helps anyone else, the "--supertent" option in the command
provided should probably be "supratent".

Tom

On Mon, Apr 25, 2011 at 3:44 PM, Douglas Greve <gr...@nmr.mgh.harvard.edu>wrote:

>  Here are two that were suggested by anothers on the FS list:
>
> Winkler AM, Kochunov P, Blangero J, Almasy L, Zilles K, Fox PT,
> Duggirala R, Glahn DC. Cortical thickness or grey matter volume? The
> importance of selecting the phenotype for imaging genetics studies.
> Neuroimage. 2010 Nov 
> 15;53(3):1135-46.http://www.ncbi.nlm.nih.gov/pubmed/20006715
>
>
> Cerasa et al., Dysbindin C-A-T haplotype is associated with
> thicker medial orbitofrontal cortex in healthy population. Neuroimage 2011
>
> You might also look at Voets, Hough et al., 2008
>
> As for your other question, it's been a while since I looked at a 4.2 stats 
> file. There are some things that look wrong in the steps that you have given. 
> The aseg.stats file from 4.2 should have had something in the header to 
> indicate the total white matter volume. Probably the easiest thing to do is 
> to run the version 5 mri_segstats program on your version 4.2 data, something 
> like:
>
>
> cd $SUBJECTS_DIR/yoursubject
>
> mri_segstats --seg mri/aseg.mgz --sum stats/new.aseg.stats --pv
> mri/norm.mgz --empty --excludeid 0 --excl-ctxgmwm --supertent --subcortgray
> --totalgray --in mri/norm.mgz --in-intensity-name norm --in-intensity-units
> MR --etiv --surf-wm-vol --surf-ctx-vol --ctab
> $FREESURFER_HOME/ASegStatsLUT.txt --subject yoursubject
>
> This will create "new.aseg.stats". In the header of this file you will find
> Total Gray and Total White volume measures.
>
> doug
>
>
>
> On 4/25/11 12:44 PM, Thomas Ballinger wrote:
>
> Hello,
> I've been asked to obtain freesurfer volume measurements on some cases
> we've already run with Freesurfer for comparison to VBM measurements.  Can
> anyone direct me to any literature or briefly share knowledge about
> comparing these two methods?
>
> Second question:
> For said analysis, I'd like to get the total white and grey matter volume
> from the Freesurfer cases.  The cases were run with Freesurfer 4.2, so I
> don't have access to some of the tools I'm found referenced in discussions
> of finding total grey matter in the mailing list archives.  How does this
> look for a total grey matter method?  somewhat taken from
> http://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg10468.html
>
>    1. Get total supratentorial (i.e. sans cerebellum) WM+GM volume.
>    ("BrainSegVolNotVent" in wmparc.stats)
>    2. Get cerebral WM volume.  (wmparc.stats reports the value of total
>    cerebral white matter volume)
>    3. Subtract 2 from 1 to get total supratentorial GM volume.
>    4. Get whole brain GM and WM volumes by adding in cerebellar
>    volumes.(wmparc.stats L/R Cerebellum WM/Cortex)
>    5. Calculate total CSF volumes by summing the individual ventricle and
>    "other" CSF values.(calculate from aseg.stats or wmparc.stats by summing
>    *-Lateral-Ventricle, *-Inf-Lat-Vent, 3rd-Ventricle, 4th-Ventricle, CSF, and
>    5th-Ventricle)
>
> Thanks very much to anyone with time to respond,
>
> Thomas Ballinger
> Research Assistant at PNL at BWH
>
>
>
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