Freesurfer's estimate of ICV ("eTIV") is designed to be insensitive to
brain atrophy -- after all, it is an estimate of "intracranial volume",
not brain volume.  See the Buckner et al. (2004) paper for a validation
of this.

cheers,
-MH

On Fri, 2011-04-08 at 17:04 -0500, Gonzalo Rojas Costa wrote:
> Hi:
> 
>    I have an MRI of a 34 years old patient that have a brain atrophy, 
> but with freesurefer I got an ICV of 1120 cc that is near the normal 
> size for her age... I review the talairach transform, but I think it is 
> ok... What could be the problem ?... Could I upload the MRI volume ?...
> 
>    Sincerely,
> 
> 

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