Hi Anne

I suspect that if you removed enough manually it would change. The 
atlas-based registration will change if the skull-stripping changes 
significantly, which will change the resulting segmentation.


cheers
Bruce


On Sun, 20 Mar 2011, Hendrikx, A.A.E.M. (Anne) wrote:

> Dear all,
>
> We, members from the Donders Institute Nijmegen (The Netherlands), are using 
> FreeSurfer to calculate amygdala volumes on MRI's. After a couple of tests we 
> are suprised about the following:
>
> We are wondering why the amygdala volume changes, after changing the 
> watershed threshold. Besides, if we should nog change the ws-treshold, but 
> manually remove remaining skull, the amygdala volume will not change.
>
> We don't understand this. Can anyone explane this to us? And besides, what 
> consequences are there for the accuracy of the calculations?
>
> Best wishes,
>
> Anne Hendrikx
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>
>
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