Hi Mira, If the map you provided is of uncorrected p-values at say p=0.05, then you appear to have just a couple small regions of group differences, so it isn't surprising that after FDR nothing would survive.
The result is what it is, and unless you had specific a priori hypotheses regarding regions that would be involved (i.e., to which you could restrict your testing), then there isn't much you can do. cheers, -MH On Fri, 2010-10-22 at 14:53 -0700, Mira Michelle Raman wrote: > Hi, > I have a dataset that seems to have some very nice group differences > (please see the graph and qdec image), but they never seem to survive FDR. I > noticed when I run the "Set Using FDR", it generates a very high threshold > above 5; where as, with some of my other datasets FDR is set much lower > (often in the 2's and 3's). Can you please give me some insight into why the > threshold is being set so high? Is it solely linked to the small sample size, > or is there something additional we can do in the processing, so that regions > with such large group differences will survive correction? > > Thank you, > Mira > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to whom it is > addressed. If you believe this e-mail was sent to you in error and the e-mail > contains patient information, please contact the Partners Compliance HelpLine > at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
