Hi,

To run bbregister outside of the recon stream, I tried:
setenv SUBJECTS_DIR /autofs/space/brownie_003/users/gcoombs/SUBJECTS_DIR
cd $SUBJECTS_DIR
bbregister --mov mri/nu.mgz --int ../mni305.cor.mgz --reg 
mri/transforms/talairachTEST.xfm --init-spm --t1 --s amac_TEST --tmp ./TEMP

but when I tried to view it with: 

tkregister2 --mov amac_TEST/mri/nu.mgz --fstal --reg 
amac_TEST/mri/transforms/talairachTEST.xfm --surf orig --s amac_TEST

It looks the same as it did before, and I am concerned that the bad tal 
registration will affect the localization of fMRI data and ICV measurements. 
Does anyone have any advice on how to fix the registration?

Thanks,
Garth

> 
> -- 
> 
> On Tue, 16 Mar 2010, Garth Coombs wrote:
> 
>> Hi,
>> 
>> I recently ran into a problem with some of my tal registrations during the 
>> recon-all process (see below message to Martino's Tech). In order to fix the 
>> problem, it was suggested that we run bbregister outside of the recon-all 
>> stream and then feed that registration into the subsequent recon stages. 
>> Does this make sense, and how would I go about doing this? I'm not sure what 
>> the --mov file should be, or if there is a way to specify fstal as the 
>> reference structural.
>> 
>> Thanks for your help!
>> 
>> -Garth
>> 
>> Hi Doug & FreeSurfers,
>> 
>> I recently re-ran a large number of recons and have been checking to make 
>> sure
>> they all ran correctly, and I have come up with a couple of questions about 
>> the
>> talairach transform/recon checking.
>> 
>> For some of my recons, the green line outlining the white matter on the
>> individual brain extends slightly further than the cortex surface of the 
>> fstal
>> brain. While it looks relatively well aligned (e.g. ventricles, brain stem), 
>> the
>> fstal brain looks slightly too small for the subject's brain. Additionally, 
>> the
>> green outline tends to extend into the skull of fstal in the sagittal plane. 
>> An
>> example is:
>> 
>> setenv SUBJECTS_DIR /autofs/space/brownie_003/users/gcoombs/SUBJECTS_DIR/
>> tkregister2 --mgz --fstal --surf orig --s amac_anat
>> 
>> or
>> 
>> tkregister2 --mgz --fstal --surf orig --s amra_anat
>> 
>> In order to fix these talairach transforms, it seems like the best option 
>> would
>> be to scale the brain; however, we will be doing a cortical thickness 
>> analysis
>> on this group, and we do not want to scale the brain if it will somehow 
>> affect
>> the outcomes. Is this something we should worry about?
>> 
>> Another question we have is about general recon quality control: when 
>> checking
>> that the recons ran smoothly, what should we look for? I look to make sure 
>> that
>> the pial and white matter surface lines don't include dura or any other 
>> matter
>> and that they follow the structures correctly, skull stripping, and intensity
>> normalization, but is there anything else that is particularly important?
>> 
>> Any advice would be greatly appreciated!
>> 
>> Thanks,
>> Garth
>> 
> 
> 

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