Hi, in our population of MCI patients, unfortunately parts of the cerebellum were not completely scanned. I ran the data throught the whole FS-4.5.0 pipeline and I see that the eTIV normalized volumes of the segmented structues have very large variance compared to the eTIV normalized group of independent age matched subjects with the full brain coveage. I assume that this is possibly due to the suboptimal registration to the template, which is used to compute eTIV. In fact, all the subjects with incomplete cerebellum failed to pass the quality check of the registration to Talairach, but on the first glance the registration seemed fine to me so I just used -notal-check flag to complete recon-all -all.
I know I could go back, check more carefully and correct the Talairach transform manually, but I hesitate to go this way. Rather I thougt if it would be possible/feasible to remove the cerebellum from each subject AND the template and possibly achieve better registration from these images. Thanks in advance for opinions, Martin _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
