Hi Cindy,

this is on our to-do list. Maybe David can give you an update as to where we are?

cheers,
Bruce


On Thu, 4 Mar 2010, Cindy Eckart wrote:

Dear FreeSurfers,

I plan to do a cerebellar volume analysis in a rather large clinical sample and 
thereto originally aimed to follow the instructions of Makris and colleaugues 
(2003, 2005). Unfortunatly I was not able to get access to all the necessary 
software and accordingly I am forced to improvise and find another solution. 
Thus I have a lot of questions:

 

1. I learned from the mailing list archive that there already have been several 
requests concerning that topic and that there also have been some plans for 
labeling parts of the cerebellum (according to an email from David Salat, 
07/09/2008)... have any of this plans been completed yet? Because I certainly 
do not want to reinvent the wheel ;-) .....

 

2. If not.... to keep as close as possible to the procedures described in 
Makris and colleaugues (2003, 2005), I originally planned to inflate the 
surface of the cerebellum (they quote in their papers that there might be a way 
to do that with Freesurfer, when the cerebellum is segmented in its grey and 
white matter as it is meanwhile implemented in the conventional aseg 
procedure??); then I wanted to create a cerebellar parcellation atlas according 
to its gyral and sulcal pattern in a subset of subject and finally hoped to be 
able to process the rest of my population largely automatically with the help 
of this new atlas... does this seem reasonable? And do anyone have experience 
with tasks like that?

 

3. But then, I learned again from the mailing list archive that surface 
extraction of the cerebellum is that hampered (due to the comprehensible 
resolution issues), that it is completely disadvised. Instead it was 
recommended (if any) to include respective volume labels in the aseg procedure 
and to do a volumetric analysis. Is this right? And are there any instructions 
how I could do that?

 

4.As I do not have any experience in tasks like that and sometimes tend to 
overrate myself (;-)) do you think that it might in principal be feasible to do 
a automatic cerebellar volume analysis or would I generally be better of in 
trying to do it manually?

 

Thank you (again :-))  very much for your advise!!

 

Kind regards

Cindy
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