freesurfer has what is called the 'longitudinal' processing stream which
is intended for exactly this purpose.  you will need v4.5.0 of
freesurfer, as that version of recon-all contains the hooks to do this
type of analysis.

for complete details on how this works, see:
https://surfer.nmr.mgh.harvard.edu/fswiki/LongitudinalProcessing

n.


On Fri, 2010-02-12 at 18:10 -0300, Gonzalo Rojas wrote:
> Hi:
> 
>    I have three MRIs of the same patient taken at different 
> dates/years... I need to compare the hippocampus volume (for example) 
> between the three MRI... I want to compare also the cortical thickness 
> between the three MRI... How can I do such computation ?...
> 
>    Sincerely,
> 
> 
> Gonzalo Rojas Costa
> Department of Radiology
> Las Condes Clinic
> Santiago
> Chile
> 
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> Freesurfer@nmr.mgh.harvard.edu
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> 
> 

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