I think your constraint of 5-7 null time is too tight for optseq, and 
you may still have too much time in your run to make 5-7 work. It's hard 
to say whether the VRFAvg is good enough or not. You are using sub-TR 
estimation during the optimization. If you are going to assume a shape 
to the HRF, then it's probably fine. If  you are going to use an FIR, 
then you'd need about 7 runs or so.

doug

杨宏宇 wrote:
> Hi Doug,
>
> I reduced the total time points, however, I found the eff and VRF 
> value all became smaller as the time points decreased, and I still got 
> some null events more than 7s. If I set the time points as 470s, I got 
> most 5-7 null events, except the last 35s null event, and then its eff 
> is 0.007, and VRFAvg is 1.7. Compared with 500 time points (eff 0.01, 
> VFRAvg 2.58), 470s is bad design. From one paper, I learned that 
> exponential distribution produced less variance compared with unity 
> distribution, and maybe optseq2 likes exponential distribution more, 
> so can I use the 470s design without the last 35s null events? Is the 
> value of eff and VFRAvg OK?
>
>
> ......
> ......
> 819.0000    5   13.000   1.0000       diamond
> 832.0000    0    5.000   1.0000          NULL
> 837.0000    2   13.000   1.0000          star
> 850.0000    0    5.000   1.0000          NULL
> 855.0000    2   13.000   1.0000          star
> 868.0000    0    5.000   1.0000          NULL
> 873.0000    3   14.000   1.0000          star
> 887.0000    0    6.000   1.0000          NULL
> 893.0000    4   12.000   1.0000       diamond
> 905.0000    0   35.000   1.0000          NULL
>
>
>
>     On Tue, Oct 20, 2009 at 11:59 AM, Douglas N Greve
>     <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
>
>         I think this is partially a bug in optseq and partially a
>         problem with your design. You have a total amount of
>         stimulation time = 12*9+13*8+14*8+12*9+13*8+14*8 = 648 sec.
>         Your run lasts 500*2 = 1000 sec, so the total amount of
>         fixation time is 1000-648 = 352 sec. You have 8*4+9*2 = 50
>         stimuli, so the average time between stimuli (ie, average
>         null) will be 352/50 = 7.04s. Yet you have constrained optseq
>         to give you nulls between 5 and 7 sec. You need to relax this
>         constraint or reduce the total number of time points.
>
>         doug
>
>         杨宏宇 wrote:
>
>             Hi list,
>
>             I am using optseq2 to design my fMRI study. These are my
>             scripts:
>
>             optseq2 --ntp 500 --tr 2 --psdwin 0 40 1 --ev star 12 9
>             --ev star 13 8 --ev star 14 8 --ev diamond 12 9 --ev
>             diamond 13 8 --ev diamond 14 8 --tnullmin 5 --tnullmax 7
>             --nkeep 3 --o ex.event12.13.14s --nsearch 5000
>
>             I have 2 events, which last for 12,13, and 14s. I found
>             that the schedule documents I got had many null events
>             more than 7s, however, I have set the maximam as 7s. In
>             the sum logfile, I found that my script was recorded
>             correctly, so could you please tell me the reason, and how
>             to solve the problem?
>
>             Many thanks,
>             Hongyu
>             Division on Addiction,
>             Psychiatry Department,
>             UT Southwestern Medical Center
>
>             
> ------------------------------------------------------------------------
>
>             _______________________________________________
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>
>
>         -- 
>         Douglas N. Greve, Ph.D.
>         MGH-NMR Center
>         gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>         Phone Number: 617-724-2358 Fax: 617-726-7422
>
>         In order to help us help you, please follow the steps in:
>         surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>         <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
>
>
>
>
>

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

In order to help us help you, please follow the steps in:
surfer.nmr.mgh.harvard.edu/fswiki/BugReporting


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