Dear all,
 
1-Is there a way to use mris_anatomical_stats
to calculate mean ROI values on the re-sampled and smoothed individual
subject data that is produced in the pre-processing step, rather than
mapping the ROI back to each subjects’ space? If so what is the
command?
 
2-If you define a ROI where there is
statistically significant difference (between 2 groups) at the group level
on your average subject and then map the ROI back to each subject’s
space and measure the mean value of say thickness in that ROI, should you
expect to find the same significant difference between the groups that you
are comparing? What does it mean if you don’t for some ROIs?
 
3- Is there a way to smooth the vertices in a ROI similar to
what is done at the preprocessing level?

4- There is a comment
on wiki (qdec, ROI analysis) that indicates the usefulness of mapping
the ROI back to each ubject's space to 'check the integirty
of your reults'. Could you please elaborate more on this? 
 
Thank you,
Nasim
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