On 10/06/2009, at 9:51 PM, Toh Hock Wong wrote:

Hi all,
I have reconstructed 12 paediatric subjects aged 4-13 and managed to load qdec as well as generating stats. The factors are age, diagnosis, gender and a continuos factor such as lh temporalpole thickness. When i click analyze, the return is a list of errors as follow.
UseMaskWithSmoothing     1

OneSampleGroupMean 0

y /Applications/freesurfer/subjects/qdec/ lh_temporalpole_thickness/y.mgh

logyflag 0

usedti  0

FSGD /Applications/freesurfer/subjects/qdec/ lh_temporalpole_thickness/qdec.fsgd

labelmask /Applications/freesurfer/subjects/fsaverage/label/ lh.cortex.label

maskinv 0

glmdir /Applications/freesurfer/subjects/qdec/ lh_temporalpole_thickness

DoFFx 0

Creating output directory /Applications/freesurfer/subjects/qdec/ lh_temporalpole_thickness

Loading y from /Applications/freesurfer/subjects/qdec/ lh_temporalpole_thickness/y.mgh

Matrix condition is 1e+08

ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08

Possible problem with experimental design:

Check for duplicate entries and/or lack of range of

continuous variables within a class.

1.000   0.000   0.000   0.000   3.701   0.000   0.000   0.000;

 0.000   0.000   1.000   0.000   0.000   0.000   4.554   0.000;

 1.000   0.000   0.000   0.000   4.044   0.000   0.000   0.000;

 0.000   0.000   1.000   0.000   0.000   0.000   4.459   0.000;

 0.000   0.000   1.000   0.000   0.000   0.000   3.857   0.000;

 0.000   0.000   1.000   0.000   0.000   0.000   3.537   0.000;

 0.000   0.000   1.000   0.000   0.000   0.000   3.652   0.000;

 1.000   0.000   0.000   0.000   2.870   0.000   0.000   0.000;

 0.000   0.000   1.000   0.000   0.000   0.000   3.736   0.000;

 0.000   0.000   1.000   0.000   0.000   0.000   3.636   0.000;

 1.000   0.000   0.000   0.000   4.102   0.000   0.000   0.000;

 1.000   0.000   0.000   0.000   3.755   0.000   0.000   0.000;

 0.000   0.000   0.000   1.000   0.000   0.000   0.000   2.816;





Error in Analyze: command failed: mri_glmfit --y /Applications/ freesurfer/subjects/qdec/lh_temporalpole_thickness/y.mgh --fsgd / Applications/freesurfer/subjects/qdec/lh_temporalpole_thickness/ qdec.fsgd dods --glmdir /Applications/freesurfer/subjects/qdec/ lh_temporalpole_thickness --surf fsaverage lh --label /Applications/ freesurfer/subjects/fsaverage/label/lh.cortex.label --C / Applications/freesurfer/subjects/qdec/lh_temporalpole_thickness/ contrasts/lh-Avg-Intercept-thickness.mat --C /Applications/ freesurfer/subjects/qdec/lh_temporalpole_thickness/contrasts/lh-Avg- thickness-lh_temporalpole_thickness-Cor.mat --C /Applications/ freesurfer/subjects/qdec/lh_temporalpole_thickness/contrasts/lh-Diff- nonepileptic-epilepsy-Intercept-thickness.mat --C /Applications/ freesurfer/subjects/qdec/lh_temporalpole_thickness/contrasts/lh-Diff- nonepileptic-epilepsy-Cor-thickness-lh_temporalpole_thickness.mat -- C /Applications/freesurfer/subjects/qdec/lh_temporalpole_thickness/ contrasts/lh-Diff-Male-Female-Intercept-thickness.mat --C / Applications/freesurfer/subjects/qdec/lh_temporalpole_thickness/ contrasts/lh-Diff-Male-Female-Cor-thickness- lh_temporalpole_thickness.mat --C /Applications/freesurfer/subjects/ qdec/lh_temporalpole_thickness/contrasts/lh-X-diagnosis-gender- Intercept-thickness.mat --C /Applications/freesurfer/subjects/qdec/ lh_temporalpole_thickness/contrasts/lh-X-diagnosis-gender-Cor- thickness-lh_temporalpole_thickness.mat

What do i need to do from here?

Do i have to write a fsgd file/contrast etc? Any suggestions will be most appreciated!

If i wish to use freesurfer for a paediatric group less than 10 years old, what errors or difficulties should i be anticipating?

Thanks!                     Toh Wong







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