We have build a normative base with 68 subjects sampled from the average brazilian population.
we are really interested in conducting / cooperating in a multicenter study. Enviado do meu celular Nokia -----Msg original----- De: Dana W. Moore Enviada: 13/05/2009 18:46:08 Para: freesurfer@nmr.mgh.harvard.edu Assunto: [Freesurfer] Re: Literature values for cortical thickness Actually, I have also been looking for cortical thickness normative values. We have run our first few research subjects with FreeSurfer (a normal control and several patients with neurodegenerative disorders), and I wanted to see if the thickness values we're getting are in the normal range. I have two papers: Salat et al. (2004) and Fischl & Dale (2000) in Cerebral Cortex. The Fischl and Dale gives average thickness for gyral and sulcal regions. Am I correct to guess that the average gyral and sulcal regions are taken by averaging the individual gyral and sulcal units from the aparc.a2005s.stats files? The Salat et al. article gives a global thickness measure--I was wondering how I would calculate this? Also, if thickness values are available for individual parcellation units and/or whole lobes, that would be very helpful as well. In particular, the lobes would be helpful, as well as ROIs most relevant for AD (e.g. entorhinal cortex and temporal pole [Desikan et al., 2009]). Thanks, Dana > > >---------------------------------------------------------------------- > >Message: 1 >Date: Wed, 13 May 2009 08:54:59 -0400 (EDT) >From: ra...@nmr.mgh.harvard.edu >Subject: Re: [Freesurfer] Literature values for cortical thickness >To: "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> >Cc: freesurfer@nmr.mgh.harvard.edu, Falk L?sebrink > <falk.lu...@gmx.net> >Message-ID: > <49194.70.23.239.45.1242219299.squir...@mail.nmr.mgh.harvard.edu> >Content-Type: text/plain;charset=iso-8859-1 > >Hi Falk, > >We do indeed have cortical thickness values for each of the parcellation >units for a range of subjects (healthly elderly, middle age and young >controls and Alzheimer's disease subjects). Which parcellation units are >you looking for? A whole lobe? > >Best, > >rahul > > > Hi Falk, > > > > we published some values in our Cerebral Cortex paper , but I suspect the > > effective thickness will vary a bit as a function of pulse sequence, and > > certainly it will vary with things like age. Rahul has probably tabulated > > by parcellation unit if that helps. > > > > cheers > > Bruce > > > > On Wed, 13 May > > 2009, Falk Lüsebrink wrote: > > > >> Hi everyone, > >> > >> > >> > >> As I dont do a study in which I compare a group of subjects with some > >> kind > >> of abnormality with a control group I was looking for literature values > >> for > >> cortical thickness. The only paper I found which was written by von > >> Economo > >> et al. in 1925 doing a post-mortem analysis. > >> > >> > >> > >> Are there any more recent sources available which maybe even cover > >> in-vivo > >> values for regional cortical thickness? Actually Im looking for average > >> values across the whole lobes. > >> > >> > >> > >> Thanks in advance, > >> > >> Falk > >> > >> > > > >------------------------------ > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
