Hello,

I'm performing a study with 10 controls to be compared with 2 groups of
dementia patients, each with 10 subjects as well. I now need to create an
average subject for the study, but I'm not sure if I should include the 30
subjects, only the 10 controls, or have two averages, each with 20 subjects
(controls+cohort1 and controls+cohort2). What would you say is the least
biased/more robust approach?
Thank you!

Joao Pereira

-----Original Message-----
From: [EMAIL PROTECTED]
[mailto:[EMAIL PROTECTED] Behalf Of Bruce Fischl
Sent: 15 August 2008 04:11
To: Nick Schmansky
Cc: Freesurfer Mailing List; ??
Subject: Re: [Freesurfer] edit white matter


actually I wouldn't worry about it. It's not cortical. Might be the optic
radiation, but it will have no effect on anything you want to do. If you
don't like the way it looks you could erase the wm voxels that make it up,
but I wouldn't bother.

On Thu, 14 Aug 2008, Nick Schmansky wrote:

> It is a defect of some kind.  Use the save point / goto feature of
> tksurfer and tkmedit, as described in the tutorial, to see discover the
> cause of the defect.  That is, click on a point on that needle in
> tksurfer, click save point, then click goto point in tkmedit, after
> loading the brainmask and whitematter surfaces.  Probably some dura is
> remaining.
>
> Nick
>
>
> On Fri, 2008-08-15 at 10:52 +0800, ÿÿÿÿ wrote:
>> Hi
>>   I have run the recon-all -autorecon2  command  and I checked the
>> inflate surface, it seems like something like a needle on the surface,
>> Is this normal?
>> I paste some pictures in the accessory, and by the way, I checked the
>> white matter surface and pial surface and they seems all right.Can
>> somebody tell why
>> there is a needle on the surface? Thanks in advance.
>>
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