Hi Paul,
Just as an aside, once you have a talairach_with_skull.lta file (whether
from v3 or v4), you can calculate eTIV as scale_factor/determinant(lta),
where the scale_factor employed is 2150.

Incidentally, using the -eTIV option of mri_label_volume, you can also
specify other transforms (e.g., talairach.xfm, talairach.lta) to be used
used instead of the default talairach_with_skull.lta in computing "ICV".
I've looked at the effect of using different transforms in a handful of
brains, and "ICV" can vary a bit depending on transform you choose to
use.

I'm curious: Has anyone out there compared FS's ICV estimate to ICV
estimated by another program?

Best,
Mike H.


On Fri, 2008-06-20 at 14:35 -0700, Paul Greenberg wrote:
> Hello Freesurfers,
> 
> I am interested in comparing eTIV calculated with version 3.0.5 to
> that calculated by version 4.0.5 (64 bit Cent OS).  
> 
> In order to compare eTIV for a single brain estimated in version 3.0.5
> to version 4.0.5, I copied a subject's previous freesurfer output
> (v3.0.5) into the freesurfer version 4.0.5 folder, deleted all the
> files within the "transforms" folder and carried out the following
> procedures as outlined in the recon-all dev table:
> 
> 1)  Run the talairach procedure.  Command =  talairach_avi --i
> mysubject --xfm talairach.auto.xfm
> 2)  cp talairach.auto.xfm talairach.xfm
> 3)  Run automatic failure detection.  Command=  talairach_afd -T 0.005
> -xfm talairach.xfm   
> 4)  Create talairach_with_skull.lta.  Command =  
>         mri_em_register -skull nu.mgz
> $freesurferhome/average/RB_all_withskull_2007-08-08.gca
> talairach_with_skull.lta
> 5)  Check the new eTIV.  Command = 
>         mri_label_volume -eTIV talairach_with_skull.lta aseg.mgz 17 53
>         As the aseg.mgz file exists from previous processing (versio
> 3.0.5), and the talairach_with_skull.lta was re-created with the new
> processing (version 4.0.5), the output of this command should list the
> eTIV based on the new talairach transform?
> 
> Are these procedures correct for generating new values of eTIV if that
> is all i want? 
> 
> Thanks!
> 
> -- 
> 
> Paul Greenberg, Ph.D.
> Radiology Department, University of California, San Diego
> VA San Diego Healthcare System (116A-13)
> 3350 La Jolla Village Drive
> San Diego, CA  92161
> Phone: (858) 552-8585 ext. 2903
> Fax:  (858) 642-3836
> [EMAIL PROTECTED] 
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
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