Hi Hae-Jeong,

most of the details of mri_normalize are given in the recon1 paper in NeuroImage, 1999 (Dale et al). It shifts the wm intensity, and the gray comes along with it, so it won't change the g/w contrast.

cheers,
Bruce


On Thu, 20 Sep 2007, Hae-Jeong Park wrote:

Dear Freesurfer Helpers,

I think 'mri_normalize' might play an important step for the cortical
thickness measurement.
However, I could not find much information regarding 'mri_normalize' except
for a brief description as below:
"mri_normalize converts orig or nu volume from cortical reconstruction as
input into a new volume where white matter image values all range around
110"

It only explains the level of white matter but not the intensity level of
the gray matter which is also important to segment them.
Is the intensity normalized proportionally or just shifted to make white
matter level 110?

By looking at argument lists for mri_normalize, I could guess the process
but I need some confirmation about how it works.
Any reference or detailed explanation on procedures for mri_normalize would
be greatly appreciated.


Hae-Jeong
MoNET
Yonsei University

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