Hi,
I was trying to figure out if there is any way to determine the exact
size at which clusters becomes significant given a specified
significance, and it appeared from the mc-corrected overlay that in this
overlay the clusters do not continously change in size but appear
discretely at a given threshold and are the same size at higher
thresholds in an all-or-nother sort of way. I take this to mean that
because the monte carlo simulation was performed at a given threshold,
the clusters at that threshold size are corrected for mutiple
comparisons based on the probability distribution of the chance data
(though I don't know the details). Because it is done in this way, it
seems I would either have to run several monte carlo simulations, at
successively higher minimum thresholds, in order to arrive at the
critical cutoff sizes for significance. This is impractical, so I guess
my question is, does the way in which the monte carlo simulations are
done preclude the possibility of getting the cluster sizes at which they
will have a certain CWP value, or is there some way of doing this?
Thanks,
Rob
--
Robert P. Levy, B.A.
Research Assistant, Manoach Lab
Massachusetts General Hospital
Charlestown Navy Yard
149 13th St., Room 2611
Charlestown, MA 02129
email: [EMAIL PROTECTED]
phone: 617-726-1908
fax: 617-726-4078
http://nmr.mgh.harvard.edu/manoachlab
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