Hi Aaron,

don't bother looking at the orig - look at the white and pial instead. The pial in your image looks fine.

Bruce
On Tue, 21 Mar 2006, Goldman, Aaron (NIH/NIMH) [C] wrote:

Hi, I'm using stable 3.0 with the recon-all -all command (so whichever atlas is the 
default for lh.aparc.annot). I'm not sure if this is what your 2nd question is asking, 
but the pial outlines do tend to "cross under" the orig slightly (as shown 
above). I kind of assumed this was normal though.

Anyway, I've looked at some more, and when I look at the orig surface I think 
most of ours look like the image Greg posted. Were you able to answer his 
question (if so, I don't think it went to the list)? Thanks,

Aaron

-----Original Message-----
From: Rahul Desikan [mailto:[EMAIL PROTECTED]
Sent: Monday, March 20, 2006 2:20 PM
To: Goldman, Aaron (NIH/NIMH) [C]
Cc: Greg Harris; Freesurfer Mailing List; Karl Helmer
Subject: RE: [Freesurfer] Re: ventral cingulate sulcus labeled 'corpuscallosum' 
with skull-stripped orig data

Hi Aaron,

Which version of Freesurfer and which version of the parc atlas are you
using? Also have you checked your surfaces along the midline to see if
they are acting in a strange way (i.e. self-intersecting, crossing the
midline, etc.)?

thanks,

Rahul

On Mon, 20 Mar 2006, Goldman, Aaron (NIH/NIMH) [C] wrote:

Hi, I think I may have observed the same issue he's talking about. What I've attached is 
possibly an extreme example (I haven't inspected many yet, to be honest), but it seems 
typical for at least a bit of this to happen in our subjects. I was also curious if the 
black "unknown" label was expected to extend into the temporal lobe as it does 
here.

Thanks,

-Aaron-

-----Original Message-----
From: Rahul Desikan [mailto:[EMAIL PROTECTED]
Sent: Saturday, March 18, 2006 5:51 PM
To: Greg Harris
Cc: Freesurfer Mailing List; Karl Helmer
Subject: [Freesurfer] Re: ventral cingulate sulcus labeled 'corpuscallosum' 
with skull-stripped orig data

Hi Greg,

Could you send along jpegs or rgbs detailing what excactly the
parcellation atlas is doing in the cingulate region? Also have you looked
at both the white and pial surfaces in this area?

Hope you are well othwerwise,

Rahul

On Sat, 18 Mar 2006, Greg Harris wrote:

Dear Karl,

Has anybody had any success with the midline rois given by the atlas
curvature.buckner40.filled.desikan_killiany that is automatically applied
by autorecon3 under the newest stable release, version 3.0?

Our trouble lies in the regions labeled corpuscallosum and
<anything>cingulate: this
atlas is giving us a corpus callosum that is exactly the ventral cingulate
sulcus, and the 4
cingulate gyrus segments, which is what we are interested in in this case,
incorrectly
exclude their ventral portion.

I presume this has been made to work at mgh, because Rahul Desikan's paper
contains
an illustration that is anatomically correctly labeled for these regions.

We are providing an orig/001.mgz image to the autorecon1 step that is
talairach aligned,
skull stripped, and resampled to 1.0 mm voxels, but otherwise is a signed
16-bit
T1-weighted MRI scan.  We have thousands of them, collected over the past 15
years.
We are writing a nifti .nii file, and converting it with

mri_convert -it nii -ic 128 128 96 -oc 128 128 96 -iid -1.0 0.0 0.0
/raid1/structural/MR/9517294/0036195/10_ACPC/0036195_10_T1_brain.nii
/raid1/data/methods/atlas/parcel/lobes/cloud_study/clipped_atlas_hand_masks/iowa_cortex_atlas/FreeSurfer_Subjects/IowaFifty_2005_0036195/mri/orig/001.mgz

We actually mean to numerically measure the extent -- the area and thickness,
say -- of
anatomical regions of interest including <anything>cingulate and apply
statistical tests to
these data.  A line of guff about Type I and Type II errors and what is only
presumable
when identifying anatomical rois would be of no interest, and considered
needlessly
defensive.  After all, the other 29 regions of Desikan's really great atlas
are in working
order!

Do we need to convince Rahul Desikan to release the "correct"
*h.curvature.buckner40.filled.desikan_killiany.gcs files with FreeSurfer 3.0
that correspond to his paper?

Greg Harris
The University of Iowa College of Medicine
Psychiatry NeuroImaging Lab







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