|
FDR is not a one-side-fits-all kind of thing. It's based on data, and you have to look at your data to decide what threshold you want to use. The way you interpret FDR=.05 would be to ask yourself whether you would change your conclusions if *any* 5% of the voxels you declared active where actually false. If you have a big cluster, then you probably would not worry about it. If you had several small clusters, then you might think twice. doug Sasha Wolosin wrote: Is this something you apply frequently at MGH? What FDR value would you typically require?Doug Greve <[EMAIL PROTECTED]> >>>Currently, mris_glm does not attempt to correct for multiple comparisons, though this feature will be in the next release. In the mean time, you can correct for multiple comparisons using FDR in tksurfer. Sasha Wolosin wrote:Dear all, I would like to learn more about group analysis using mris_glm. How does the program correct for the problem of multiple comparisons? Is there any way to determine the rate of false positives? Thanks, Sasha Sasha Wolosin Research Assistant Developmental Cognitive Neurology Kennedy Krieger Institute 707 N. Broadway Baltimore, MD 21205 ph: (443) 923-9270 [EMAIL PROTECTED] Disclaimer: The materials in this e-mail are private and may contain ProtectedHealth Information. Please note that e-mail is not necessarily confidential or secure. Your use of e-mail constitutes your acknowledgment of these confidentiality and security limitations. If you are not the intended recipient, be advised that any unauthorized use, disclosure, copying, distribution, or the taking of any action in reliance on the contents of this information is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender via telephone or return e-mail._______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Douglas N. Greve, Ph.D. MGH-NMR Center [EMAIL PROTECTED] Phone Number: 617-724-2358 Fax: 617-726-7422 |
_______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
