A quick Google search for

2026 new industrial motherboards with PCI slot

turned up quite a number of them, and some that actually don't have 32bit PCI 
slots. One company still has some with PCI Express, PCI and ISA.
That would be kind of fun, a Core 2 Quad box with a current generation PCIe x16 
GPU and an ISA Media Vision Pro Audio Spectrum 16 soundcard.
Same company had newer Intel LGA CPU socket boards with PCI slots, and no ISA 
slots.
One catch though, most of these companies have rather eye watering prices on 
their boards.

Another possibility to look at is test if the PCI Mesa card will work with a 
PCI to PCIe adapter. They're mostly pretty low priced and available for x1 PCIe 
slots because a single PCIe 1.0 lane is almost 2x as fast as the maximum a 
33Mhz 32bit PCI slot can hit. 

On Sunday, August 23, 2026 at 03:08:53 PM MDT, [email protected] 
<[email protected]> wrote: 

What I Would Like To Know:

1. What AT/ATX (including miniature versions sharing at least 4 
screwhole locations) form factor PC motherboards that are or have the 
following features, are available:
A. Currently purchasable new from stock.
B. Low Latency (no real time errors). This probably means no onboard 
video, so a slot for a video board is needed along with BIOS setup 
options to disable fancy real-time ruining features.
C. 1 available PCI slot for the existing 5120 card.
D. Some expectation of long term reliability (if possible).
I asked Claude.ai about this, and his opinion was that the PCI slot 
support that allows reusing the 5i20 is antiquated in 2026 and that 
switching to a Pci-E or ethernet connected Mesa board would be a more 
future proof course of action. Whatever FPGA card is used needs to have 
at least 2 50 pin ribbon cable connections to preserve the existing 7i37 
and 7i47 Mesa daughter boards. Converting these boards to something else 
would cause a lot of wiring work... Something like the 7i80HD or 7i93 
for ethernet, or the 6i24 in Pci-E.

2. How about industrial ATXish motherboards that don't have slots, or 
have 1 slot for a video board, connected to the FPGA card through 
ethernet

3. It's 2026! Should I just consider switching to a Raspberry Pi (or 
other SBC) and another FPGA card from Mesa that uses an Ethernet or SPI 
interface and provides at least 2 of the Opto22 style I/O connectors?

4. The ideal situation would be a pre-integrated LinuxCNC machine that 
came in a DIN rail mountable case that could be snapped in and be ready 
to plug in the existing USB, HDMI, network, and Mesa ribbon cables and 
24Vdc or 90-250Vac power. If anyone knows of something like this...

I'd love to hear about how people are handling this aspect of things, 
especially if a consensus has developed around a particular hardware 
configuration.

Thanks,
Matt


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