Hi Daan, Sorry I did not notice that you were using devcloud for testing. The fresh 4.2.1 installation should be ok. However, the issue may impact the upgrade. vhd-util was in /opt/xensource/ directory in 4.2, so /opt/cloud/bin/vhd-util may be missing after upgrade to 4.2.1. I do not have xenserver testing environment, hope someone can help.
-Wei