I did a little bit of more triaging: Staying on my Linux acer07 4.8.0-21-generic #23-Ubuntu SMP Tue Oct 4 18:27:25 UTC 2016 x86_64 x86_64 x86_64 GNU/Linux and only upgrading from "nvidia-304 304.131-0ubuntu5" to "nvidia-304 304.132-0ubuntu1" brings up this problem.
On the other hand, staying on "nvidia-304 304.131-0ubuntu5" and doing a complete "apt-get dist-upgrade" otherwise, results in a completely functioning system. So looks like this problem is more connected with nvidia-304 versions than kernel versions. My workaround is (thanks to BTRFS allowing me to boot into various snapshots and having the earlier driver version available): $ cat /etc/apt/preferences.d/nvidia-304_mtrr-prob.pref Package: nvidia-304 Pin: version 304.132-0ubuntu1 Pin-Priority: -1 -- You received this bug notification because you are a member of Desktop Packages, which is subscribed to nvidia-graphics-drivers-304 in Ubuntu. https://bugs.launchpad.net/bugs/1634802 Title: Could not insert module Status in nvidia-graphics-drivers-304 package in Ubuntu: In Progress Status in nvidia-graphics-drivers-304 source package in Yakkety: Triaged Bug description: Ubuntu release: 16.10 Yakkety Yak Kernel version: 4.8.0-22-generic x86_64 Package version: 304.132-0ubuntu1 The nvidia module cannot be loaded. The following errors are reported: Could not insert module Unknown symbol in module and: nvidia: Unknown symbol mtrr_del (err 0) nvidia: Unknown symbol mtrr_add (err 0) It looks like the buildfix_kernel_4.3.patch, which is supposed to be dealing with those calls, is not applied in this release of the package. The package was working fine with the previous fully updated Ubuntu version 16.04 prior to the upgrade to 16.10. To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/nvidia-graphics-drivers-304/+bug/1634802/+subscriptions -- Mailing list: https://launchpad.net/~desktop-packages Post to : desktop-packages@lists.launchpad.net Unsubscribe : https://launchpad.net/~desktop-packages More help : https://help.launchpad.net/ListHelp