I had to stop using junkbuster a while ago because Mozilla really didn't like using it. Something about http 1.0 and 1.1, but for a long time Mozilla just plain didn't work with proxies. I ended up doing some work arounds to keep the ads from getting too annoying.
Obviously, use the Mozilla cookie management stuff. I think this is one of the best features of Mozilla. Block ads from dedicated ad servers using the Mozilla image loading management. I right click on ads, select copy image location, paste that into a scratch buffer and if it is something like ads.annoying.com then I right click on the image and select block images. The previous step only blocks some ads because many load from www.someplacegood.com/ads or something that Mozilla's simple blocking model can't handle. To deal with these I turned off animated gifs in Mozilla. There might be an easier way to do this, but this method works. Open libnsgif.so with a hex editor (emacs hexl-find-file) and search for NETSCAPE2.0 and change a letter or two of that string. Make sure you keep the same number of characters though. The gif library looks for this string in gifs, and if it finds it then the gif animation is looped forever, but if the string is not found the animation is played once and stopped. Since doing these things I really haven't missed junkbuster.