Yeah, you've answered your own question.  In practice, I doubt the
difference is measurable.

Another common idiom you see in Clojure code is:
(defn f [xs]
  (if-let [s (seq xs)]
    ...do something with (first s) and (f (rest s))...
    ...base case...))

This ensures that you seq-ify the input (rather than assuming it has been
seq'ed before passed in), gives you the fast test against nil, and uses
rest rather than next because next would have the effect of causing an
extra unnecessary call to seq.

In a loop-recur situation, it is more common to do the seq once in the
initialization of the loop and then use next which calls seq:

(defn f [xs]
  (loop [s (seq xs)]
    (if s
       ... (recur (next s))...
       ... base case ...)))


Out of habit, I prefer to see the base case first so I don't usually do
either of these, but these two patterns are a very popular style, and very
fast execution.  If you don't have a pre-existing preference, these would
be good choices.

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