I think that if you're wanting to do this then you probably are taking the
wrong approach, but taking you at face value I would say try something like
this.  If you provide more information on what you are actually trying to
do, then you might be able to get better advice.

(defmacro def-onto-concept [name-sym desc-str name-str]
  `(onto/defconcept ~name-sym ~desc-str ~name-str))

(doseq [[name-sym desc-string name-string] (prepare-data spreadsheet)]
  (def-onto-concept name-sym desc-string name-string))

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