I've been considering the same trade-offs recently. I looked at 
ClojureScript->RN but found the levels of indirection, the heavy number of 
libraries and lack of concurrency (important on mobile devices) make me 
unenthusiastic. I've also looked at Flutter (& DartLang) but coming from 
Clojure I wasn't excited about Dart, and Flutter also similarly lacked 
concurrency. 

I landed on good ol' C++, bridged by Dropbox's djinni interface DSL + 
tooling (https://github.com/dropbox/djinni). Performance & compatibility 
were all there, plus it allows me more freedom to make trade-offs about 
what parts of my app are implemented in shared code - and what's 
implemented directly in native (ObjC/Swift or Java/Kotlin) or using 
libraries only available in those languages. Being C++, I should be able to 
use Scheme or Common Lisp though I haven't tried yet.

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