In any such discussion, I'll heavily favor matrix.org. To me,
decentralization seems inevitable and I hope that it will already carry,
what marketers will be calling web 3.0. Current matrix.org infrastructure
is only semi-decentralized (similar to xmpp), but the data model is already
built with full decentralization in mind and current matrix clients are
already pretty complete and user friendly.

That said, I'm not aware of any existing Clojure/ClojureScript integration,
but I fathom it would be natural to just use
https://github.com/matrix-org/matrix-js-sdk from ClojureScript.

Also, have a look at the Clojure Community channel (bridged to a slack
channel): https://riot.im/app/#/room/#clojure-community:matrix.org
and the IRC bridge channel: https://riot.im/app/#/room/#clojure:matrix.org

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