To me this looks like a mixture of oxidized and reduced states of the S-S bond. Hard to say with any certainty seeing as the (optical) resolution is modest.
Artem - Cosmic Cats approve of this message On Mon, Mar 17, 2025 at 8:18 AM Devbrat Kumar <devformed...@gmail.com> wrote: > Hello Everyone, > > I am worried about the density of the disulfide bond in the cryo-EM > structure that I am analyzing. The experimental map shows the expected > density for the disulfide bond involving two cysteine residues, but in > addition, I see some unexplained density, which I do not know how to > interpret. > > I have attached the figure for your reference. Does anyone have experience > with such extra density around a disulfide bond in their structures? Any > thoughts would be greatly appreciated. > > Thanks for your attention and assistance. > > Warm regards > Devbrat kumar > Postdoctoral Fellow > IITD, In > > ------------------------------ > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 > ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/