Hey The method described in this reference using af2cycler that uses AlphaFold2’s intrinsic denoising capabilities combined with Protein MPNN to refine seems like something you might want to read. here is a biorixv paper- https://www.biorxiv.org/content/10.1101/2024.11.21.624687v1.full *Pius Padayatti*
On Fri, Feb 28, 2025 at 10:47 AM careinaedgo...@yahoo.com < 000002531c126adf-dmarc-requ...@jiscmail.ac.uk> wrote: > Dear all > This post is a bit off topic but I wonder if anyone could help direct me > to a good tool to use for designing novel peptides with affinity for a > certain protein? > Kind regards Careina > > > > ------------------------------ > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 > ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
