You need Protein MPNN, otherwise you’ll just get a poly-glycine chain

Jürgen 
_______________________________________________
Jürgen Bosch, PhD, MBA
Center for Global Health & Diseases
Case Western Reserve University
Cleveland, OH 44106
https://www.linkedin.com/in/jubosch/

CEO & Co-Founder at InterRayBio, LLC



> On Feb 28, 2025, at 1:57 PM, Abhishek A. Jalan <rendezvous.a...@gmail.com> 
> wrote:
> 
> RFdiffusion is a good starting point. 
> Best, 
> Abhishek
> 
> On Fri, Feb 28, 2025 at 7:47 PM careinaedgo...@yahoo.com 
> <mailto:careinaedgo...@yahoo.com> 
> <000002531c126adf-dmarc-requ...@jiscmail.ac.uk 
> <mailto:000002531c126adf-dmarc-requ...@jiscmail.ac.uk>> wrote:
>> Dear all
>> This post is a bit off topic but I wonder if anyone could help direct me to 
>> a good tool to use for designing novel peptides with affinity for a certain 
>> protein?
>> Kind regards Careina
>> 
>> 
>> 
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