We need a few more details. What is the spacegroup? Maybe the hexamer is
generated by the spacegroup symmetry. Molecular replacement finds the
contents of the asymmetric unit and leaves it up to you to decide on the
oligermetric structure.
the program PISA will analyse that for you..
\Eleanor

On Fri, 28 Feb 2025 at 10:52, CENGIZ KAAN FERAH <
0000a9b927892eef-dmarc-requ...@jiscmail.ac.uk> wrote:

> Hello,
>
> There's something that I'm currently struggling with in terms of Molecular
> Replacement and Refinement. From my mtz file, my solutions unit cells are
> consistent with PDB entries of homologous structures. But when I'm trying
> to get fit in the same oligomeric structure which is hexameric it doesn't
> work on Phenix as well as CCP4 Cloud. I successfully fitted in a monomeric
> form of the protein. Can you help me with this issue?
>
> Thank you. Regards.
>
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