Hi Gloria,

Guillaume already mentioned emplace_local, so I’ll just mention that if you get 
a recent nightly build of Phenix and the latest version of ChimeraX (plus the 
Phenix UI plugin from the toolshed), you can tell it your map has symmetry, 
place a monomer, and then it will detect the symmetry and place all the 
symmetry-related copies of the monomer. (That’s assuming you imposed the 
symmetry during the reconstruction.)

It’s still under rapid development: another new feature is to be able to 
account for a part of the model you’ve already placed when placing a new 
component. To come: something much more highly automated, like Phaser, in 
placing multiple copies of multiple components all in one job.

Best wishes,

Randy

> On 26 Nov 2024, at 23:50, Gloria Borgstahl <gborgst...@gmail.com> wrote:
> 
> Hello Friends,
> We are finally using cryoEM when the crystallography got too hard!  We have a 
> crystal structure for the hexamer.  What is the easiest software tool to 
> swing a monomer or hexamer into the cryoEM density?
> Thank you, Gloria
> 
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-----
Randy J. Read
Department of Haematology, University of Cambridge
Cambridge Institute for Medical Research     Tel: +44 1223 336500
The Keith Peters Building
Hills Road                                                       E-mail: 
rj...@cam.ac.uk
Cambridge CB2 0XY, U.K.                              
www-structmed.cimr.cam.ac.uk


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