Hi,

I assume the planarity you mentioned is what is discussed in Moriarty
et al (2020) https://doi.org/10.1107/S2059798320013534

As shown there, it is known to have some deviation. In Refmac (or in
the CCP4 monomer library) it is restrained using a torsion angle with
5 degree sigma instead of the planarity restraint. You can tighten the
restraint using an even smaller sigma. The keyword could be:

restr tors include resi ARG name chi5 sigma 2.0

By the way, did you mean by "outliers" those from the PDB validation
report? I have had a feeling that their criterion is a bit too strict.
Could anyone from the PDB tell how the outlier of the ARG sidechain is
calculated?

Best regards,
Keitaro

On Thu, 17 Aug 2023 at 15:02, Vladyslav Yadrykhinsky
<[email protected]> wrote:
>
> Hello,
>
> I am refining a structure and I have ARG planarity outliers in the sidechain.
> Could someone please tell me how should I set the planarity restraint in 
> REFMAC5 (version 5.8.0403) to correct them?
>
> Should I use: plane [value1] [value2] in the advanced settings? If so, what 
> values 1 and 2 should be? My current weight restraints are 0.128....
>
> Please let me know if you need more information and I will appreciate any 
> assistance on the matter.
>
> Best regards,
> Vladyslav
>
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