Hi All,

This question is mostly for RCSB and PDBe: why are you renaming chains in the 
deposited PDB files? Why does it matter what letter is assigned to the chain? 
For 1,2 or 3 chain structures it is manageable, but for more chains and/or many 
complexes per asu this becomes quite a challenge. And if chains are similar in 
shape it is a real pain. Reading associated manuscripts and looking at those 
structures is an additive that feels unnecessary.

Thank you in advance for explaining the logic behind.

Vaheh Oganesyan, Ph.D.
[cid:image001.png@01D7CF0E.5D61A0D0]
R&D | Biologics Engineering
One Medimmune Way, Gaithersburg, MD 20878
T:  301-398-5851
vaheh.oganes...@astrazeneca.com<mailto:oganesy...@medimmune.com>


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