Hi Peer, Have you tried to model the hydroxyl O1 disordered at the carbonyl position? Check the H-bonding pattern to the end groups, this might give some clues.
Cheers, Bill Le 03/06/21 12:50, « Peer Mittl » <mi...@bioc.uzh.ch> a écrit : >I'm struggling with the electron density shown in the attachment. The >substance does not seem to come from the crystallization condition nor >from the mounting buffer. The 1.6 A maps are rather clear, because the >compound binds into the hydrophobic core, which seems to be loosely >packed. > >-Peer > > > >######################################################################## > >To unsubscribe from the CCP4BB list, click the following link: >https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 > >This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a >mailing list hosted by www.jiscmail.ac.uk, terms & conditions are >available at https://www.jiscmail.ac.uk/policyandsecurity/ ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
