Dear All,

               many of us have probably experienced that, in the diffraction
of protein ligands containing heavy atoms (cisPt, I3C, etc), the
overwhelming electron density of the metal can totally flatten that of the
light atoms around (or rather make it look insignificant).

Is anyone aware of an article/review (to use as a reference) in which this
is clearly stated/pointed out? 

Best regards

 

Vito Calderone

 

 


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