Dear Francois, provided you are not restricted to the trademark term 'microED', but open minded to include '3D electron crystallography', there are plenty of published structures of small compounds, both organic and inorganic. Several of them date back to 2005, and include complex structures like MOFs, (Xiaodong Zou, Stockholm), twinned structures (Gemmi/Mugnaioli, Pisa), and really good quality work (Parsons/Zou).
Usually, crystals are not "present in powder", they compose the powder, in particular if you use products at 99.9% purity from Sigma-Aldrich 'off the shelf' is it was put, and such powders are not amorphous (if you read bioarxiv) or 'simingly amorphous' (if you read the peer-reviewed version)... Scotch is not the same as adhesive tape, and pampers is not the same as diapers (c.f. also Gerard Bricogne's post on this bb, 29th April 2020). Best, Tim On Tue, 2 Jun 2020 10:52:45 +0200 hoh <h...@cbs.cnrs.fr> wrote: > Hi everyone > > > Pr Tamir gonen (UCLA, los Angeles) have solved (not published) few > chemical compounds structures with mircoED. And, the more important > is that crystals were present in the powder (whatever condtions to > get it (preciptation, evaporation ..). I have myself test with 2 > powders coming from Chemists, here in Montpellier, and there were > bunch of nano crystals in both powders, and both diffract at 0.6 A. > And, as the wavelenght in microED in very short , Xds or Dials (with > some specifics parameters) are working well. And ,finally, you need > only around 0.01ug of product to put on the grid (without blotting, > in dry method) with result almost warranty > > So, think about microED for small molecules.. > > FH > > ________________________________________ > François Hoh > > Centre de Biochimie Structurale, > UMR 5048 CNRS, UMR 1054 INSERM > 29, rue de navacelles > 34090 Montpellier Cedex, France. > Phone: +33 467 417 706 > Fax: +33 467 417 913 > ________________________________________ > > -- -- Tim Gruene Head of the Centre for X-ray Structure Analysis Faculty of Chemistry University of Vienna Phone: +43-1-4277-70202 GPG Key ID = A46BEE1A ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
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